About Stretch Marks

WHAT ABOUT STRETCH MARKS:

Stretch Marks (Striae Distensae) and cutaneous lesions that accompany the hormonal upheavals of the major stages of life; Puberty and pregnancy are the main causes. Today, other additional  triggering factors may be involved, such as Corticosteroids treatments and obesity. Also, more recently and more unexpectedly, Aesthetic  surgery, skin stretching due to breast and buttocks augmentation. Therefore, over 60% of women are affected by stretch marks.

Men are not spared, although, the prevalence is low: puberty, obesity, and intensive body building ( especially, the  shoulders,  torso and arms),  are triggering factors. Stretch marks develop abruptly  and progresses slowly  from a pink to violet  colour   , then to an ivory white or sometimes, nacreous  hue. They  don’t go away oh. They are  experienced as unwanted visitors  that never leaves.

Although, the exact description of stretch marks  have yet been fully understood, there are four determining facts;

  • High use or abuse of corticosteroids:.  All the findings indicate a strong correlation between endogenous  Glucocorticoid secretion and the emergence of stretch marks . The activities of corticosteroids causes the growth of both  Keratinocytes and Fibroblasts  to  As is their synthesis of Collagens 1 and 111, 90% less than normal skin. In addition, Fibronectin is synthesis is reduced; 93% less than  normal skin.
  • The Early Inflammatory Stage:

A study, including young  persons  during puberty,  presenting with incipient stretch marks showed that stretch marks biopsy specimen were the site of inflammation displaying Granulocyte-Macrophage colony stimulating factor (CSF)  and Monocyte – Chemoattractant Protein (MCP). This is accompanied by visible  Elastolysis  triggered by Mast cell degranulation with release of Trypsin  and Chymotrypsin.

 

What cosmetics treatment of these tissues alterations can do are;

. Prevention of appearance and Propagation on the one hand,

. Repair of some of the tissues damage on the other hand.

 

They are based on limiting the effect of Mast cell released Trypsin and Chemotrypsin and Macrophage induced  Elastolysis by Elastase as well as helping Fibroblast to repair the matrix.

These are the basic functional pathways of  EDEN ANTI-STRETCH MARKS

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